Four-Site Intradermal Postexposure Boosters in Previously Rabies Vaccinated Subjects

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Three-year experience with 4-site intradermal booster vaccination with rabies vaccine for postexposure prophylaxis.

For booster vaccination of previously immunized persons with potential exposure to rabies, the World Health Organization recommends 2 doses of cell-culture vaccine administered intramuscularly or intradermally on days 0 and 3. We believe that four 0.1-mL intradermal booster doses given on a single day could be used at no risk to the recipient. We studied use of a single booster vaccination on d...

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Cellular immune response following pre-exposure and postexposure rabies vaccination by intradermal and intramuscular routes

PURPOSE Immunization against rabies in humans induces protective neutralizing antibodies; however, the induction of type 1 or type 2 cytokine mediated cellular immune responses following rabies vaccination is not understood. Hence, the present study investigated cellular cytokine responses in vaccinated individuals. MATERIALS AND METHODS The study groups included healthy rabies antigen naive ...

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ژورنال

عنوان ژورنال: Journal of Travel Medicine

سال: 2006

ISSN: 1195-1982

DOI: 10.2310/7060.2002.23189